BOSTON, Mass. (WPRI) — Two more Massachusetts residents have tested positive for the monkeypox virus, bringing the state’s total case count to six.

The two adult males are currently isolating and the Massachusetts Department of Public Health (DPH) is working to identify anyone who may have been in contact with them while infectious.

The DPH said there is no known connection between the two new cases.

The Centers for Disease Control and Prevention (CDC) reports that so far, there have been more than 72 cases of monkeypox reported this year. There have been no deaths connected to this outbreak, as monkeypox is rarely fatal.

The United States reported its first monkeypox case in a Massachusetts man back in May. At the time, the DPH said the man had just returned from a trip to Canada.

While other early cases were also associated with international travel, the DPH said the most recent cases aren’t. Rhode Island reported its first probable case last week, which is believed to be connected to travel to Massachusetts.

The monkeypox virus isn’t easily transmissible among people. The DPH said the virus spreads through direct contact with bodily fluids and monkeypox sores, or by touching items contaminated by infected fluids. It can also be spread through respiratory droplets during prolonged face-to-face contact, though the DPH said it’s not as common.

Early signs of monkeypox infection can include fever, headache, sore throat and swollen lymph nodes. Those symptoms are typically followed by a rash on the face and body.

Most people, according to the DPH, recover from monkeypox within weeks.